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Thread: Niacin Flush and Transdermals

  1. #1
    Join Date
    Jul 2002
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    Any opinions on whether taking Niacin to induce a Niacin flush will aid in the absorption of a transdermal prohormone? Many of you probably already know that Niacin will cause an increased blood flow in the capillaries near the surface of the skin. Can we use this to our advantage? Plus, it often times will lower your cholesterol
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  2. #2
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    Mar 2002
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    That is a really good question. I have thought about that myself on many occasions.

    Still, rather than enhancing absorption, it would most likely only increase the rate that it reaches the general circulation after it has already been absorbed. Still it deserves some thought...
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  3. #3
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    Apr 2002
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    Boston Ma
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    That is a great question. I wonder if there is a dosage needed to elicit the desired response. I wonder if Par has any insight into this.

    Steve
    The building of a perfect body crowned by a perfect brain, is at once the greatest earthly problem and grandest hope of the race.
    -Dio Lewis
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  4. #4
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    Jul 2002
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    I've taken 200 mg of Niacin starting out. This causes a fairly intense reddening of my skin (I have a light complexion any way), some minor itching, and general warmth in the effected areas (for me it is back of the neck, eyebrows, upper arm and hands) within about 15-20 minutes. If taken everyday, the body will adapt of course and higher dosages will be required to ellicit the response. If you cycle one day on one day off, then it doesn't appear that your body will adapt. Also, the time release version of Niacin will not give this effect. Sorry if I'm telling you things you already know! I haven't tried this with prohormones yet, but I just bought some One + so I may give it a shot. Thanks for the responses!
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  5. #5

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    there is a big thread on niacin for transdermals at www.bdcnutrition.com/forum
    230lb 15 year old
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  6. #6

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    I don't think it would help, because the androgen will already partition into the bloodstream and be taken away readily (and we know this because basically all of an active is taken up by the bloodstream before it gets the chance diffuse into deep tissues, under normal conditions, so the backup (i.e. rate limiting step) is not happening here.

    It happens in the aqeous layers of the dermis, which obviously are not conducive to the diffusion of a lipophilic androgen.
    ParDeus
    M&M #7 -- Sept. 19th
    www.mindandmuscle.net
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