My gym has a Hammer strength 45 degree incline leg press machine. Previously I always used their v-squat machine for doing calves, but on Friday it was busy with a couple guys that were doing like 100 sets, so I decided to try out the leg press instead. My calves got a great workout and I can tell you that I'll never go back to the V-squat.
I've never actually used a Leg press machine, I prefer just to do real squats, so it took a little getting used to; for example, I didn't realize I had to lock the weight when I wanted to stop, and dang near crushed myself on my first set
Although, I do feel kind of silly loading up over 1000 lbs, but it wasn't much better on the v-squat machine, there I was around 600.