MS itself recommends sticking to a certain rep total throughout an entire cycle, and I believe it's 20 reps. So if you believe in utilizing the different rep ranges, then simply use MS to get to 15, 10, 5, etc.
I value the endurance I gain from continuous reps, even if it sacrifices extra hypertrophy that strict-MS might offer. But, I definitely believe MS is a great tool for busting out extra reps. I tinkered with it a bit early on in my cycle. If I wanted to get say, 15 reps. I would get what I can using conventional reps. If I couldn't get all 15, I'd finish off the rest with MS... kind of getting the best of both worlds. I usually stopped about 2 reps to failure before hitting it with MS.
Then again, there are exercises like DL's, where I use MS to nearly it's fullest. There is no re-racking required. I just really don't see how someone can stick to 20 total reps, then when they get to high weight like their 5 rep max, using MS effectively on something like squats. The idea of unracking, getting set, doing a rep, and re-racking 20 times seems a bit tedious.
But hey, until I ever do it myself I won't bash on it, I just seem skeptical about MS when it comes to some applications of it's use.
As for m-time, I believe Dan even said that m-times of less than 30 seconds is optimal. Personally, I would go with whatever m-time you feel it takes to get the next rep at full-blast. So it will more than likely change throughout a given set. I'm not sure as to how sticking with a set m-time would fair.. would be interesting to know. I think sci did that, but I don't remember what he said about it.