Satellite Cells, Nuclei And Ribosomes

Discussion in 'Hypertrophy-Specific Training (HST)' started by NWlifter, Dec 1, 2021.

  1. NWlifter

    NWlifter Active Member

    I can't find the old thread where we were talking about satellite cells, and I remember Bryan posted in the thread that ribosomes might be even more important. This study kinda ties that together. That additional myo-nuclei might actually be generating more ribosomes, rather than just creating more contractile proteins.

    https://journals.physiology.org/doi/abs/10.1152/ajpcell.00358.2021

    "we provide evidence that satellite cell-derived myonuclei may preferentially supply ribosomal proteins to growing myofibers"
     
    _Simon_ likes this.
  2. Old and Grey

    Old and Grey Super Moderator Staff Member

    I see that there must be at least two ghosts roaming the graveyard. How about a short paragraph, Ron, summarizing the gobbledygook in remedial English. ‍♂️
     
  3. NWlifter

    NWlifter Active Member

    LOL yep, I'm the Ghost of Science Past lol

    Pretty much that sentence summed it up,

    "we provide evidence that satellite cell-derived myonuclei may preferentially supply ribosomal proteins to growing myofibers"
     
  4. Old and Grey

    Old and Grey Super Moderator Staff Member

  5. NWlifter

    NWlifter Active Member

    LOL ok basically, the nuclei already in the cells are cranking out the code for contractile proteins, when satellite cells donate more nuclei, much of the code for proteins, are actually to build more ribosomes, then those can actually make more actual proteins (contractile and all others). Hope that makes sense :)

    It seemed before, that it was a separate process, we needed more nuclei for the contractile generation and more ribosomes to actually 'make' those proteins, but it looks like much of the donated nuclei from satellite cells, is for making more ribosomes.
     
  6. Old and Grey

    Old and Grey Super Moderator Staff Member

    Yes, much better in plain English!
     
  7. NWlifter

    NWlifter Active Member

    ok cool, I knew I could do English but plain and understandable was the challenge lol
     

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