Testosterone Receptors

mj0llnir

New Member
I have not posted in a very long time, but thought of something I thought someone on this board may have knowledge of.

About a year ago I went to my doctor regarding a feeling of being run down that had been with me for about a year.  My doctor had some tests run on my blood.   One of the test was for testosterone present in my body.  I don't remember the designation they used to quantify the testosterone.  I think it was in nano-somthing per a ml, but I can't remember.  I'm trusting that the standard quantification is known to someone who might read this post.  The doctor told me the normal range of testosterone in a male is between 200-1200.   My test was at 260, very low for my age (37).   I had a difficult time getting an appointment with an endocrinologist due to international travel in my job.   About 3 months ago I change doctors and had another blood test.  My test was still sitting at 260 and I was still experiencing general malaise.  My doctor put me on androderm 5mg patches.

Within 2 hours of applying the patch I felt 100% better.  Since then my strength, recuperation, and overall activity levels have increased dramatically.   I have always been relatively large and strong compared to other people, and had a propensity to weight lifting, but now I'm reaching new heights.

From what I've read androderm increases blood level between 300-400 points (depending on where it is applied), putting me in the mid-level range for my testosterone amount (around 800, at most).

I have read that others experiences little gains from androderm and suspect I have always had a low amount of testosterone production but have always gained weight, strength and mass relatively easy, actually exceeding the gains of some steroid users I've lifted with.  

I wondered if it is possible that my body has a large amount of testosterone receptors compared to most people and this may account for my size and strength.

The androderm patches have been burning my skin.  I have bright red patches on my skin where I apply the patches that are very itchy and rough.   I switched to androgel 3 days ago.

I have been a natural lifter from the time I was 12 years old and only now started using testosterone.   Does anyone know anything about receptor increase or decrease in response to natural lifting?

I tried searching for 'receptors' in all forums and came up with nothing.

I have read that androderm and gel generally don't work for most people.   My recuperation and general intesity while lifting are going through the roof and am looking for an explanation as to why this would be for me, but not other people.

It seems to me that test is test, and it wouldn't really matter if it is oral, injected or transdermal.
 
I can't answer your question, but if you go to Dr. Crisler forum the guys there are pretty well versed in TRT.

http://musclechatroom.com/forum/forumdisplay.php?f=2

Also, if you go to allthingsmale.com you will find some very informative information about TRT and the different medications that are available.

If you live in the Michigan area or are available to go there, I highly recommend Dr. Crisler, hell of a nice guy and his whole practice is based around TRT.

Best of Luck
 
AR mrna (Androgen receptor mrna) can and does increase with training. There are also increases in AR mrna from supraphysiological dosing of androgens.

It's not known as to how far these increases go but since sat cells do have ARs it would seem to me that increasing or rather bringing sat cells out to play would increase receptor activity as well, this is also seen in prolonged training.

How many receptors we are born with is unknown but I would venture to guess this is highly individualistic as we see some people with quite pronounced musculature and others not and neither have ever touched a weight in their lives.

As far as how is your test measured, ng/dl is one method and yes 260 is low.

I have used the gel in the past (5mg) and it did seem to help with mood and energy but really didn't do much for the weight room.

Other options are to also have your estrogen levels checked; ARs do not discriminate between Estrogen and Test they will dock with either. Total testosterone tests do not show how high your estrogen counts are. If high they may prescribe an anti-estrogen as well.
 
Back
Top