http://www.exercisebiology.com/index.php/site/articles/muscle_memory_solved/ Interesting little article here. I don't have the time or brains to parse out the research, not sure if it can even be found online. But it seems to make sense. The summary is that muscle memory is potentially the result of the cells retaining their nuclei and so being able to rebuild faster. Also mentioned is that previous studies miscounted nuclei as the muscles atrophied. It's always those pesky previous studies that suck the wind out of your sails. Anyway, I just found it interesting. If I recall the donation of nuclei by satellite cells is one of the main steps in hypertrophy and one of the things creatine may help increase. What we need of course now is methylated sub lingual super creatine with much more bioavailableness and other supplementy stuff like that.