Differences in connective tissue adaptations

Discussion in 'Hypertrophy Research' started by abanger, Nov 23, 2009.

  1. abanger

    abanger Member

    The adaptability of tendon to loading differs in men and women.
    <div>
    (Borge Fagerli @ Aug. 19 2007)</div><div id="QUOTEHEAD">QUOTE</div><div id="QUOTE">This study provides an explanation for why women are more susceptible to connective tissue damage and inflammation of the tendons and muscle attach than men. Estrogen seems to play an important role in this, and the study shows that in connection with the exercise and mechanical load, women lack the necessary adaptations in the connective tissue structures (collagen) which strengthens them. Women should be more conservative with sudden increases in loads. Instead of increasing the load each workout or week it is recommended to either take the total number of reps on a given strain (reps progression) 2-3 weeks before the load is increased.


    Int J Exp Pathol. 2007 Aug; 88 (4) :237-240.

    The adapters ability of tendon two loading differs in men and women.
    Peter Magnusson S, Hansen M, Langberg H, Miller B, Haraldsson B, Westh Kjoeller E, Koskinen S, Aagaard P, Kjær M.

    Institute of Sports Medicine Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark.

    The reason why women sustain more soft tissue injury than but during physical activity is unknown. Connective tissue properties and extra cellular matrix adapt ability in human tendon were investigated in models that addressed biochemical, physiological and biomechanical aspects of tendon connective tissue in response to mechanical loading. Habitual training resulted in a larger patellar tendon in but but not in women. Following an acute bout of exercise, but had an elevated tendon collagen synthesis rate and this effect was less pronounced or absent in women. Moreover, levels of circulating estrogen affected the acute exercise-related increase in collagen synthesis. Finally, the mechanical strength of isolated tendon collagen fascicles in but surpassed that of women. Thus, compared to men, women have (i) an attenuated tendon hypertrophy response to habitual training; (ii) a lower tendon collagen synthesis rate following acute exercise; (iii) a rate of tendon collagen synthesis which is further attenuated with elevated estradiol levels ; and (iv) a lower mechanical strength of their tendons. These data indicate that tendons in women have a lower rate of new connective tissue formation, respond less two mechanical loading, and have a lower mechanical strength, which may leave the tissue more susceptible two injury.</div>
     

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