Here are some studies you can read on wound healing.
Hunt TK, Hussain MZ.
Can wound healing be a paradigm for tissue repair?
Med Sci Sports Exerc. 1994 Jun;26(6):755-8..
[b said:
Quote[/b] ]This paper is written in the hope, if not the conviction, that it will be helpful to investigators of muscle physiology and development. Its thesis is that cell growth, connective tissue matrix deposition, and angiogenesis are stimulated in wounds in response to NAD+ depletion caused by a burst in lactate generation. We surmise that muscle development may also involve this metabolic control.
Hunt TK, Knighton DR, Thakral KK, Goodson WH 3rd, Andrews WS
Studies on inflammation and wound healing: angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages.
Surgery. 1984 Jul;96(1):48-54.
Hunt TK, Conolly WB, Aronson SB, Goldstein P.
Anaerobic metabolism and wound healing: an hypothesis for the initiation and cessation of collagen synthesis in wounds.
Am J Surg. 1978 Mar;135(3):328-32.
[b said:
Quote[/b] ]Total LDH activity corresponded directly to lactic acid concentration and inversely to oxygen availability. LDH isoenzymes in wound fluid were in an anaerobic pattern soon after injury and evolved toward the aerotic pattern as oxygen supply more nearly matched metabolic capacity. Lactate levels in the wound space are elevated soon after wounding and remain elevated far above those in blood. These data again indicate that wound metabolism is characterized by a relatively poor oxygen supply. Current data from several sources indicate that lactate found in the hypoxic area of the wound may stimulate collagen synthesis in fibroblasts lying in the high lactate environment. We postulate that elevated concentration of lactate in wounds is a major signal for collagen synthesis and repair.
BTW, even though I'm in Houston I gotta say, AUSTIN ROCKS
