Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet.
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(Borge Fagerli @ Feb. 13 2009,2:01)</div><div id="QUOTEHEAD">QUOTE</div><div id="QUOTE">Here is a recently completed study that directly shows what can be achieved by following Health & Fitness Concept - diet:
It could certainly have been several subjects and a longer time horizon, but it is quite dramatic results after just 10 days! Lower insulin levels, blood pressure, LDL cholesterol and triglycerides and improved insulin sensitivity ...
Eur J Clin Nutr. 2009 Feb 11
Metabolic and physiologic improvements from consuming a Paleolithic, hunter- Gatherer type diet.
Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC Jr, Sebastian A.
1Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Background: The contemporary American diet figures centrally in the pathogenesis of numerous chronic diseases-'diseases of civilization '. We investigated in humans whether a diet similar to that Consumed by our preagricultural Hunter-Gatherer ancestors (that is, a Paleolithic type diet) confers health benefits. Methods: We performed an Outpatient, metabolically controlled study, in nine nonobese sedentary healthy volunteers, ensuring no weight loss by daily weight. We compared the findings when the participants Consumed their usual diet with those when they Consumed a Paleolithic type diet. The participants Consumed their usual diet for 3 days, three ramp-up diets of increasing potassium and fiber for 7 days, then a Paleolithic type diet Comprising lean meat, fruits, vegetables and nuts, and excluding nonpaleolithic type foods, such as cereal grains, dairy or legum, for 10 days. Outcomes included arterial blood pressure (BP); 24-h urine sodium and potassium excretion, plasma glucose and insulin areas under the curve (AUC) during a 2 h oral glucose tolerance test (OGTT), insulin sensitivity, plasma lipid concentrations, and brachial artery reactivity in response to ischemia.Results: Compared with the baseline (usual) diet, we observed (a) significant reductions in BP associated with improved arterial distensibility (-3.1 + / -2.9, P = 0.01 and 0.19 + / -0.23, P = 0.05), (b) significant reduction in plasma insulin vs hour AUC, during the OGTT (P = 0.006), and © large significant reductions in total cholesterol, low-density lipoproteins (LDL) and triglycerides (-0.8 + / -0.6 (P = 0.007), -0.7 + / -0.5 (P = 0.003) and -0.3 + / -0.3 (P = 0.01) mmol / l respectively). In all these measured variables, either eight or all nine participants had identical directional response when switched two Paleolithic type diet, that is, near consistently improved the status of circulatory, carbohydrate and lipid metabolism / physiology.
Conclusions: Even short-term consumption of a Paleolithic type diet improves BP and glucose tolerance, decreases insulin secretion, increases insulin sensitivity and improves lipid profiles without weight loss in healthy sedentary humans.
Read also this slightly older thread - here you will find several studies ...</div>
<div>
(Borge Fagerli @ Feb. 13 2009,2:01)</div><div id="QUOTEHEAD">QUOTE</div><div id="QUOTE">Here is a recently completed study that directly shows what can be achieved by following Health & Fitness Concept - diet:
It could certainly have been several subjects and a longer time horizon, but it is quite dramatic results after just 10 days! Lower insulin levels, blood pressure, LDL cholesterol and triglycerides and improved insulin sensitivity ...
Eur J Clin Nutr. 2009 Feb 11
Metabolic and physiologic improvements from consuming a Paleolithic, hunter- Gatherer type diet.
Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC Jr, Sebastian A.
1Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Background: The contemporary American diet figures centrally in the pathogenesis of numerous chronic diseases-'diseases of civilization '. We investigated in humans whether a diet similar to that Consumed by our preagricultural Hunter-Gatherer ancestors (that is, a Paleolithic type diet) confers health benefits. Methods: We performed an Outpatient, metabolically controlled study, in nine nonobese sedentary healthy volunteers, ensuring no weight loss by daily weight. We compared the findings when the participants Consumed their usual diet with those when they Consumed a Paleolithic type diet. The participants Consumed their usual diet for 3 days, three ramp-up diets of increasing potassium and fiber for 7 days, then a Paleolithic type diet Comprising lean meat, fruits, vegetables and nuts, and excluding nonpaleolithic type foods, such as cereal grains, dairy or legum, for 10 days. Outcomes included arterial blood pressure (BP); 24-h urine sodium and potassium excretion, plasma glucose and insulin areas under the curve (AUC) during a 2 h oral glucose tolerance test (OGTT), insulin sensitivity, plasma lipid concentrations, and brachial artery reactivity in response to ischemia.Results: Compared with the baseline (usual) diet, we observed (a) significant reductions in BP associated with improved arterial distensibility (-3.1 + / -2.9, P = 0.01 and 0.19 + / -0.23, P = 0.05), (b) significant reduction in plasma insulin vs hour AUC, during the OGTT (P = 0.006), and © large significant reductions in total cholesterol, low-density lipoproteins (LDL) and triglycerides (-0.8 + / -0.6 (P = 0.007), -0.7 + / -0.5 (P = 0.003) and -0.3 + / -0.3 (P = 0.01) mmol / l respectively). In all these measured variables, either eight or all nine participants had identical directional response when switched two Paleolithic type diet, that is, near consistently improved the status of circulatory, carbohydrate and lipid metabolism / physiology.
Conclusions: Even short-term consumption of a Paleolithic type diet improves BP and glucose tolerance, decreases insulin secretion, increases insulin sensitivity and improves lipid profiles without weight loss in healthy sedentary humans.
Read also this slightly older thread - here you will find several studies ...</div>