What is best for increasing dopamine ?

Caffeine acts as an antagonist of adenosine, which acts at certain presynaptic receptors to inhibit the release of some neurotransmitters such as glutamate and dopamine. Since caffeine blocks the effects of adenosine, there is an increase in the release of dopamine.

L-Tyrosine is a precursor to dopamine, but it is doubtful if it leads to a direct increase in dopamine - studies are inconclusive in this regard. It will, however, increase catecholamine levels. I suspect supplementation would help you had l-tyrosine deficiency, which is unlikely though.

Same goes for pyridoxine (B6) - I doubt it would affect dopamine levels unless you have a deficiency.

So caffeine seems to be your best bet.
 
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