I
imported_dkm1987
Guest
I originally posted in another thread about Protein Pulse Feeding an article by Bryan in Think Muscle.
This naturally spiked my curiousity so I began digging a little deeper.
So upon further digging I found out more. Not so much about the pulse feeding, although I am citing from that study, but also about protein ingestion as a whole.
Influence of the protein digestion rate on protein turnover in young and elderly subjects.
Dangin M, Boirie Y, Guillet C, Beaufrere B.
The digestion rate of protein is an independent regulating factor of postprandial protein retention.
Dangin M, Boirie Y, Garcia-Rodenas C, Gachon P, Fauquant J, Callier P, Ballevre O, Beaufrere B.
Slow and fast dietary proteins differently modulate postprandial protein accretion.
Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B.
Type and timing of protein feeding to optimize anabolism
Mosoni L, Mirand PP.
Amount and fate of egg protein escaping assimilation in the small intestine of humans.
Evenepoel P, Claus D, Geypens B, Hiele M, Geboes K, Rutgeerts P, Ghoos Y.
From the way I see it Leucine, nitrogen balance and inhibited proteolysis is favorable with the prolonged effect of cassein, unless you are old.
Ok, with all that posted, here is my question.
Is it better to use cassein throughout the day and forget about whey as a pre workout?
And please state why with study references if you have them. Not from the FAQ since I have read all of those a multitude of times.
This naturally spiked my curiousity so I began digging a little deeper.
So upon further digging I found out more. Not so much about the pulse feeding, although I am citing from that study, but also about protein ingestion as a whole.
Influence of the protein digestion rate on protein turnover in young and elderly subjects.
Dangin M, Boirie Y, Guillet C, Beaufrere B.
[b said:Quote[/b] ]Indeed, in young men, using a non-steady-state approach and intrinsically labeled milk protein fractions [whey protein (WP) and casein (CAS)] we showed that a slow digested dietary protein (CAS) induced a greater protein gain than a fast one (WP). The mechanisms of this gain also differed according to the protein rate of digestion. WP stimulated amino acid oxidation and protein synthesis without modifying proteolysis, whereas CAS increased amino acid oxidation and protein synthesis to a lesser extent and strongly inhibited proteolysis.
The digestion rate of protein is an independent regulating factor of postprandial protein retention.
Dangin M, Boirie Y, Garcia-Rodenas C, Gachon P, Fauquant J, Callier P, Ballevre O, Beaufrere B.
[b said:Quote[/b] ]The fast meals induced a strong, rapid, and transient increase of aminoacidemia, leucine flux, and oxidation. After slow meals, these parameters increased moderately but durably. Postprandial leucine balance over 7 h was higher after the slow than after the fast meals
Slow and fast dietary proteins differently modulate postprandial protein accretion.
Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B.
[b said:Quote[/b] ]Postprandial protein synthesis was stimulated by 68% with the WP meal and to a lesser extent (+31%) with the CAS meal. Postprandial whole body leucine oxidation over 7 h was lower with CAS (272 +/- 91 micromol.kg-1) than with WP (373 +/- 56 micromol.kg-1). Leucine intake was identical in both meals (380 micromol.kg-1). Therefore, net leucine balance over the 7 h after the meal was more positive with CAS than with WP (P < 0.05, WP vs. CAS). In conclusion, the speed of protein digestion and amino acid absorption from the gut has a major effect on whole body protein anabolism after one single meal. By analogy with carbohydrate metabolism, slow and fast proteins modulate the postprandial metabolic response, a concept to be applied to wasting situations.
Type and timing of protein feeding to optimize anabolism
Mosoni L, Mirand PP.
[b said:Quote[/b] ]PURPOSE OF REVIEW: The delivery rate of amino acids to an organism significantly affects protein anabolism. The rate can be controlled by the type and the timing of feeding. Our aim was to bring new insights to the way they may act. RECENT FINDINGS: During young and adult ages, when food supply is liberal, subjects can adapt to various modes of protein feeding. However, during food restriction, protein anabolism is favored when the delivery of amino acids is evenly distributed over the day, either with frequent meals, or through the use of slowly absorbed proteins like casein. In contrast, during aging, quickly absorbed protein sources become more efficient. During recovery after exercise, the timing of protein feeding after the end of exercise may or may not influence its anabolic effect, depending on the subject's age and the type of exercise. SUMMARY: The synchronization of variations in anabolic capability with amino acid supply partly explains the effects of the type and timing of protein feeding. This effect is modulated by the amount of amino acids required to increase whole-body proteins and by the signaling properties of some amino acids to stimulate protein synthesis. Indeed, the anabolic effect of amino acids is determined by their interaction with other anabolic factors (other nutrients or physiological factors, whose efficiency is mainly related to their effect on protein degradation). It is clear that benefits can be obtained from adapted protein feeding patterns.
Publication Types:
Review
Review, Tutorial
Amount and fate of egg protein escaping assimilation in the small intestine of humans.
Evenepoel P, Claus D, Geypens B, Hiele M, Geboes K, Rutgeerts P, Ghoos Y.
[b said:Quote[/b] ]Ten healthy volunteers were studied once after ingestion of a cooked test meal, consisting of 25 g of (13)C-, (15)N-, and (2)H-labeled egg protein, and once after ingestion of the same but raw meal.Amounts of 5.73% and 35.10% (P < 0.005) of cooked and raw test meal, respectively, escaped digestion and absorption in the small intestine. A significantly higher percentage of the malabsorbed raw egg protein was recovered in urine as fermentation metabolites. These results 1) confirm that substantial amounts of even easily digestible proteins may escape assimilation in healthy volunteers and 2) further support the hypothesis that the metabolic fate of protein in the colon is affected by the amount of protein made available.
From the way I see it Leucine, nitrogen balance and inhibited proteolysis is favorable with the prolonged effect of cassein, unless you are old.
Ok, with all that posted, here is my question.
Is it better to use cassein throughout the day and forget about whey as a pre workout?
And please state why with study references if you have them. Not from the FAQ since I have read all of those a multitude of times.