I'm not sure if this has already been covered but just a thought: Obviously, heavy partials will place more load on any joints being used for a movement. If you use them exclusively you will have a far greater likelihood of developing joint wear/damage/pain over time. That seems like a foolish thing to do if you plan on maintaining weight-training as a part of your lifestyle. On the other hand, using partials at the end of a cycle, for a week or so, maybe for a few exercises, would seem like a much more sensible way of utilising them; but, in order to use partials effectively for muscular hypertrophy, you would need to have dialled in your form for full-ROM movements first. If you don't, you could easily fall into the trap of cheating your muscles out of doing work by using a form which primarily stresses your connective tissue and joints. That won't help with load progression for the targeted muscle tissue at all. The other problem, as I see it, with jumping into partials at an early stage in your lifting career, as well as using them for multiple exercises, is that it will likely not allow time for your connective tissue, cartilage etc. to toughen up enough. Depending on how partial your partials are, you will be able to use loads way in excess of what you would be able to manage for full-ROM movements. So, if a heavy set of 5 reps has the potential to make your joints ache, then a much heavier set of partials will most likely be worse. IMHO, partials are a more advanced training tool and, as such, trainees should really know what they are doing before introducing them into their training.