I realize this thread is a little old, but...
Ketones are produced in the liver as a sort of side effect of overwhelming the aerobic cycle ("TCA" during gluconeogenesis. (Some, but not all, of the brain's metabolism can run off ketones, but it needs glucose.)
Not right, no. The brain (and CNS in general) requires glucose.[b said:Quote[/b] ]my perhaps flawed understanding is that in the absence of glucose, the brain needs ketones for fuel, and the muscles need free fatty acids. is this not right?
Ketones are produced in the liver as a sort of side effect of overwhelming the aerobic cycle ("TCA" during gluconeogenesis. (Some, but not all, of the brain's metabolism can run off ketones, but it needs glucose.)