Bryan, What Are Your Thoughts On Higher Frequency Training?

Discussion in 'Hypertrophy-Specific Training (HST)' started by Renky, Jun 8, 2017.

  1. NWlifter

    NWlifter Member

    I agree, I believe DOMS can be an indicator, and might provide some insight to RBE. Most studies that look at RBE look at DOMS and 'damage', and how once RBE is in effect, DOMS doesn't occur. Yet, hypertrophy still can occur. In fact, I'd venture to say that DOMS might prevent hypertrophy as post PS is more about repair and alterations than it is about hypertrophy that leads to CSA gains.

    Increasing load while maintaining volume: That yes, for sure. When you do that, you are increasing work and the TTI of the work. Same number of contractions with a heavier load is more work. Now if load was key, by itself, then just using more load, even with less volume would increase the stimulus.
    ie, in reverse order of stimulation. 12 reps with 12RM least, 8 with 8 RM more stimulus, 6 with 6 RM even more stimulation, 1 rep with 1RM would be highest stimulation.
  2. Old and Grey

    Old and Grey Super Moderator Staff Member

  3. NWlifter

    NWlifter Member

    That's a great article, I've read that before, seems pretty much accurate IMO.
  4. Bryan Haycock

    Bryan Haycock Administrator

    Wow, great thread!

    I just wanted to add one thing. When thinking about load vs work, it should not be overlooked that mechanical strain triggers anabolic signaling whether the muscle is actively contracting or not. Cellular components such as membrane and extracellular matrix bound proteins like costameres, intregrins, G protein-coupled receptors have all been shown to be activated in response to being mechanically distorted (i.e. stretched). This does not negate anything that anybody has said to this point, I just wanted to point out that mechanical loading of the the tissue (i.e. stretch) does initiate anabolic signaling pathways independent of the work the tissue is doing. Furthermore, these "mechanosensors" do become less sensitive to mechanical distortion as part of the adaptive process of the muscle cell to mechanical strain.
  5. Old and Grey

    Old and Grey Super Moderator Staff Member

    Ergo the problem. The longer we work out, the tougher any sort of gains.
  6. NWlifter

    NWlifter Member

    Good post Bryan!

    Here is the thing that has bothered me for many years..... really think about this, maybe you have some thoughts on it.
    People tend to think we 'put a load' on a muscle fiber, but we don't. It 'creates tension'.
    So a fresh fiber in tetany can 'create some exact' tension (sum of cross bridges in parallel)
    I've read that almost all human movement, especially under load, is tetanic contracts. Force is varied by rate coding and synchronization of the motor units. Almost like the lights blinking on a Christmas tree.
    That means, if I lift a 5Rm or an 8Rm anytime a fiber 'is active', it's in tetany and putting out it's tetanic force. The same force. The 5Rm just has more motor units 'on' at the same time, more often to sum up to a higher total muscle force.
    You can see what bothers me then, if all that physiology is true, then each muscle fiber 'creates/feels' the same absolute tension with different loads, they are just creating it more often or 'on' for longer blinks of time.

    IF that is true, it would be like having 100 digital people, each with a rope, all the ropes attached to a load. If the load was 1000 lbs, you might need 60 our of 100 pulling with full force at any point in time to support it. If the load was 1500 lbs, you might need 75 people, pulling with that same full force at any point in time to support it. Either way, each person still only would pull and 'feel' the same individual 'part' of the load. Does that make sense?

    Thoughts about that?
    Last edited: Jan 26, 2018
  7. _Simon_

    _Simon_ Member

    Ah interesting, could you please elaborate on that thanks Bryan? Are you saying that simply undergoing sufficient resistance itself (the body's structure as a generality, even if the muscle tissue isn't contracting much or at all) is sufficient? Because all the surrounding ligaments, cellular structures etc are undergoing stress, that it still brings about the anabolic signalling?
    This sort of a ties in with the other thread I just brought up.

    But I'm confused what you mean.. I'm trying to understand it in a more direct application I guess hehe. I did think that the muscle had to be contracting to oppose the load for there to be any mechanical strain and therefore anabolic growth..

    And that it's moreso important that the tissue undergoes something (just resistance with enough frequency, then obviously adaption will occur hence the need to progress), and not so important the amount of work done? Sort of makes sense, what's important is just that something/mechanical strain is occurring, and that it's a sliding scale as to what that something is (depending on current training adaptions).

    I'm just throwing around ideas, happy to be corrected haha. Thanks Bryan
  8. Bryan Haycock

    Bryan Haycock Administrator

    Hey NWlifter. I understand your thinking. I may not be able to answer this question fully, but I think I can shed some light on what really happening to relieve you of some stress. :)

    Does a fiber generate its own "load"?

    Yes, but its more complicated than that. Keep in mind that all the fibers are connected. So when one fiber contracts, all of the fibers around it are pulled and stretched by virtue of their connectedness both at the level of the extracellular matrix, and connective fascia. So, even if a fiber is not actively contracting, it is experiencing passive stretch (and distortion of its membrane) when loads are applied to the tissue. The mechanosensors in the cell membrane are then activated turning on anabolic signaling pathways.

    Is a contracting fiber in tetany?

    No, not unless you are dead. Let’s use the tug-o-war example. In a normal tug-o-war, each “puller” grabs the rope and pulls continuously until the war is over. They may reposition their grip occasionally but it is not the rule. Actin/Myosin interactions are similar but different enough that it matters when using tug-o-war as an analogy. Actin/myosin cross bridging occurs in a cyclic manner many many times per second (i.e. the speed of a chemical reaction). I have to speak in generalities here. As long as ATP is available at the site of the cross bridge, the myosin head will immediately “let go” of the actin once its power stroke occurs. Again, this occurs in a tiny fraction of a second. So each myosin head is grabbing the actin, pulling on it for a millisecond, then letting go, and grabbing it again, etc until the waves of action potentials stop coming into the t-tubules releasing pulses of Ca2+. The amount of force the fiber develops depends on how many crossbridge cycles are occurring simultaneously. Here is a super slo-mo video

    Fiber experiences same load whether lifting 5RM or 8RM?

    Yes, to some extent this is true and for the reason you explained (i.e. more motor units + more force). However, you must then add the actual mechanical load imposed on the tissue, in addition the force the tissue is generating. This increases the physical distortion that occurs in the tissue and increases mechanotransduction signaling in all fibers. So the fiber may create the same tension, but it does not “feel” the same load when going from 8RM to 5RM.
    _Simon_ likes this.
  9. Bryan Haycock

    Bryan Haycock Administrator

    _Simon_ yes, all you have to do is stretch a muscle and it will turn on anabolic signaling including the activation of satellite cells. As mentioned in the other thread, mechanosensors in the cell membrane sense stretch and distortion of the cell membrane and they respond by activating anabolic signaling pathways in the cell.
  10. NWlifter

    NWlifter Member

    Ah ha, ok now that is one area I hadn't considered, that the whole muscle tension could pull and distort 'tissue'. That the summation of fiber force is a factor. i guess I was thinking too much on the 'per fiber' basis and what a fiber 'sees/feels/generates'.

    Tetany- This throws me? So many texts refer to 'max rate coding being synonymous with 'fused tetany', and one online physiology text I had read said basically, all human movement involves tetanic contractions? That anytime calcium floods the cell fully, (with max neural input) we have fused tetany?

    Thanks a TON for the great information! you gotta post here more, inquiring minds wanna know stuff! lol
    _Simon_ likes this.
  11. _Simon_

    _Simon_ Member

    Ahh I see, makes sense, but I did think it was moreso stretch under tension resulted in that, that the muscle had to still be contracting under load.. unless we're talking about a different type of stretch here hehe. Really appreciate it :)
  12. NWlifter

    NWlifter Member

    Hey Bryan,
    When you have time a few questions/thoughts...

    This got me thinking about a couple things....

    1) Is RBE a factor in the metabolic path? It 'kinda' seems like it might be. Even though DOMS isn't required for hypertrophy, I think it clues us into an idea, it seems DOMS appears when RBE is highly exceeded. I've had DOMS from doing something very 'metabolic' with really light loads.Then when I got used to it, no more DOMS. So even with way less load, but way higher fatigue, same movement, DOMS showed up and once adapted, it quit happening. So metabolic must be part of the RBE, adaptation areas too?

    2) Based on that, it seems like there 'could' be a 'Metabolic HST' setup. Where instead of making load primary for the continual surpassing of RBE, you could make each workout exceed RBE via metabolic increases. It 'kinda' seems like metabolic is a multiplier with mechanical. Meaning mechanical x metabolic 'semi equals' MPS. The occlusion studies make me think that, really light load but super high fatigue equaled higher load with less fatigue.
    Seems like one could do a 'fatigue step increase' over a cycle?
    Reason I'm theorizing on that, is it might be a way for people like me (with injuries that prevent ever using heavy loads) to still do 'HST'.

    This info, gave me one more thought, I think that may very well explain 'Beginner gains'.
    Beginners, once they get semi-coordinated, have so much room for neural improvements, they end up tossing more load on the bar almost every workout, so I bet they are blowing out past RBE every workout from those fast neural gains, getting a big nice rise in MPS after each. Then when those fast neural gains stop, they can't exceed RBE very much or very often so muscle gains naturally slow way down too.
    Probably also why those HIT routines work so well the first time. You get a ton of neural improvements, keep adding weight like crazy while that short period of neural gains is occurring. Plus your getting a buttload of metabolic fatigue and really momentarily reducing ATP levels. Your hitting and exceeding mechanical, metabolic and energetic pathways every workout for a few weeks to a couple months until the neural gains peak.

    Last thought/question , Re-RBE & SD

    Here is another thing I've thought about over the years.
    If take an SD, we take 2 weeks off, it makes the muscles more sensitive to load, enough so that lower the loads and going back to 15's, 'works again'. There really is no atrophy in healthy well fed humans in that time, so no losses, just re sensitization.

    OK, so 2 weeks off slowly resets RBE without losses and makes us gain from loads lighter than we were doing 2 weeks before. So if a person were to train each muscle once a week, wouldn't there be a partial SD / RBE reset built into the lower frequency? So the muscle would be more sensitive and maybe get a larger effect each time? Could that be why some studies find only minor differences with training frequency when weekly volume is matched?
    3x gives you 3 small 'bumps' in MPS and the conditioning limits the level and time course, where less often gives you a bigger 'bump' that lasts longer since RBE is kind of resetting more in between each workout, so long term the results are very similar?
    Last edited: Feb 6, 2018
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  13. Renky

    Renky Member

    I agree... However, I have experimented a bit with taking longer and longer breaks from training. In my case, I have found that muscle loss was minimal and I feel that it paid dividends in spurring on new growth. I have experimented with 2 week breaks, 4 week breaks and even did a 6 week break.
  14. _Simon_

    _Simon_ Member

    Ah nice, that's good to keep in mind, rest periods seem so important, never thought of taking that long a break!
  15. Renky

    Renky Member

    I don't have any science on this... It is just something that I have played with to see what happens and I think that in my case it helped. What I have done the last few cycles (about a month out from taking a break) is to up frequency on my lagging muscle group to train the specific lagging muscle once a day, 5 days a week to twice a day, 5 days a week, to maybe even 3 times a day, 5 days a week. I keep adding frequency each week and adjust volume of course. Then I take a break, because I have learned that I cannot sustain that kind of frequency for too long. I definitely would not do this for the whole body either, just a specific muscle that I want to improve.
    I do all this with HST and myo reps.
    _Simon_ likes this.

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